| 名稱(chēng) | PARP1 p.G913fs Reference Standard 標(biāo)準(zhǔn)品 |
| 型號(hào) | CBP10450 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | PARP1 p.G913fs Reference Standard |
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基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10450PARP1 p.G913fs Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
CBP10450 | |
| Gene | PARP1 |
| Description | PARP1, poly (ADP-ribose) polymerase 1, is an enzyme that catalyzes poly (ADP-ribosyl)ation of proteins, which initiates cellular response to DNA damage (PMID: 15743666). PARP1 dysregulation has been identified in acute myeloid leukemia, breast and colorectal cancers (PMID: 25483710, PMID: 25528020, PMID: 16809031). |
| Technical Data | |
| DNA Change | c.2738delG |
| AA Change | p.G913fs |
| Mutation type | Frame_Shift_Del |
| Zygosity | Heterozygous |
| Allelic Frequency | 66.67% |
| Transcript | ENST00000366794.5 |
| Cosmic ID | N/A |
| Chr position(GRCh37) | chr1:226551692 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing | Download for COA |
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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